As the Coordinating and Operations Center (CORE) of the HIV Prevention Trials Network (HPTN), FHI is working with U.S.-based researchers and the HIV Prevention Trials Unit (HPTU) in Russia. The University of North Carolina and the State University of New York Medical Center are collaborating with the HPTU in St. Petersburg to develop and implement clinical trials and related studies of HIV prevention interventions as part of the HPTN research agenda.