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Module 6: Costing and Use of Resources

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  • How much will it cost?
  • How can resources be allocated?

There is an urgent need worldwide to increase the coverage and scope of HIV/AIDS interventions, particularly in countries where HIV is spreading rapidly. A substantial body of experience and best prevention practices have been developed during the last two decades of the HIV pandemic. Obtaining sufficient funding for proven interventions, however, has been a challenge to many countries. The good news is that financing is increasing for international HIV/AIDS programs.

Module 6, Costing and Use of Resources:

  • Provides information to assist planners and program managers in making the best use of funds received, including criteria for resource allocation and ECR cost estimates by type and capacity of HIV/AIDS program.
  • Contains tables that break down the components of various costing tasks.
  • Lists key implementation questions for costing and use of resources for ECR.
  • Provides references and resources for further reading.

Criteria for Resource Allocation

The following three criteria can help countries determine how best to allocate their resources to the priorities selected.

  • Need-based proportional allocation. This approach, often the simplest, involves allocating financial resources for HIV/AIDS interventions on a per capita basis. An example of this is in the United States, where federal HIV prevention programs are broadly allocated in direct proportion to reported AIDS cases.

    A more relevant method for developing countries may be to allocate resources on the basis of forward-looking criteria – for example, targeting social groups or communities at high risk for HIV and allocating funds to these communities on a per capita basis.

  • Institutional constraints. These types of constraints apply particularly in care and treatment. Human capacities and the health infrastructure often are used as criteria for deciding whether a specific set of care interventions can be provided. An example of how the continuum of prevention and care can look in a country is illustrated in Table 1.

  • Cost effectiveness. Resource allocation decisions generally are made on the basis of cost-effectiveness analysis. While it is ideal to use cost-benefit analysis – assessing the benefits as well as the costs of interventions – it is complex in practice and difficult to conduct.

    An important aspect of cost-effectiveness analysis is that it allows planners to rank interventions that generate comparable results. For example, in the case of workplace intervention programs, output can be measured in terms of indicators, such as how many new HIV infections and sexually transmitted infections (STIs) were avoided. By dividing these indicators by the estimated cost of other alternative programs, the cost-effectiveness ratio of interventions can be determined and ranked. (Refer to Module 2 for a detailed overview of ECR technical interventions and to Module 3 for operational strategies.)

Table 1: ECR Interventions by Need, Complexity and Cost

Essential activities

  • HIV prevention programs for target groups and youth
  • HIV voluntary counseling and testing
  • Palliative care and treatment for common opportunistic infections (OIs): pneumonia, oral thrush, vaginal candidiasis, pulmonary tuberculosis (TB) or DOTS
  • Nutritional care
  • STI care and family planning services
  • Cortrimoxazole prophylaxis for persons living with HIV/AIDS (PLHAs)
  • Community activities that mitigate the impact of HIV, including legal restrictions against stigma

Intermediate complexity and cost

All of the above plus:

  • Active case finding and treatment for TB
  • Preventive therapy for TB for PLHA
  • Systemic antifungals for systemic mycosis such as cryptococcosis
  • Treatment of HIV-associated malignancies: Kaposi's sarcoma (KS), lymphoma, cervical cancer
  • Treatment of severe herpes
  • Prevention of mother-to-child transmission (MTCT)
  • Post-exposure prophylaxis for occupational exposure to HIV and for rape
  • Reduction of economic and social impact of HIV/AIDS

High complexity and cost

All of the above plus:

  • Triple antiretroviral therapy (ARV)
  • Diagnosis and treatment of difficult-to-diagnose and expensive-to-treat OIs, such as drug-resistant TB
  • Advanced treatment of HIV-related malignancies
  • Public services to reduce the economic and social effects of PLHA

Costing Steps for ECR by Type and Capacity of HIV/AIDS Program

While there is some information on costs of community- and district-level programs and individual facilities, little exists on costs of large-scale programs. The following four steps can be used as guidelines to estimate the cost of implementing a set of HIV/AIDS interventions on a large, or national, scale.

Costing Steps for ECR on a Large, or National, Scale

Step 1: Establish Size of Target Groups

Step 2: Define Current and Future Coverage for Interventions

Step 3: Consider Existing Implementation Constraints

Step 4: Estimate Costs

ECR Costing Step 1: Establish Size of Target Groups
The first step in costing HIV/AIDS interventions for ECR is to estimate the potential target groups (PTG) to be reached by prevention and care activities. For each intervention considered, a relevant target group is defined using epidemiological, behavioral and intervention data. A list of selected target groups with their corresponding interventions is shown in Table 2.

ECR Costing Step 2: Define Current and Future Coverage for Interventions
For most interventions, existing capacity and health system infrastructure may limit the target groups that can be reached. These limits are reflected in the number of people who can be reached by the health system and the envisioned programs, and are referred to as the potential target group (PTG). The target levels of coverage reflect what is thought to be realistically achievable by 2005.

The concept of PTGs is used to ensure that the projected level of activities being planned is based on what may be feasible to implement, given current capacity and infrastructure. A model is used, based on the PTGs and projected coverage levels, to estimate the (increased) volume of activity required for each intervention to reach specific coverage targets. The box above shows how to apply the PTG concept to MTCT interventions.

Table 2: Potential Target Groups for HIV/AIDS Interventions and Activities

Intervention/Activity

Potential Target Group

Interventions for school youth and out-of-school youth

  • Male and female youth enrolled in primary schools (age 6—11)Male and female youth enrolled in secondary schools (age12—16)
  • Male and female youth aged 6—11 not enrolled in schools
  • Male and female youth aged 12—16 not enrolled in schools
  • Male and female youth enrolled in tertiary education

Sex worker interventions

  • Sex workers in urban areas

Interventions for migrant or mobile workers

  • Miners
  • Truckers
  • Farm workers

Interventions for uniformed services

  • Police
  • Armed forces (Army, Air Force, Navy, Special Forces)
  • Immigration/border control
  • Customs and excise
  • Prisons

Strengthening public sector condom distribution and Condom social marketing (male and female condoms)

  • Protection by condoms for all casual sex acts and sex acts in regular partnerships (proportion of sex acts in regular partnerships set at 2% for the analysis)

Improving STI services

  • Men (aged 15—49) with curable, symptomatic STIs and access to health services
  • Non-pregnant females (aged 15—49) with curable, symptomatic STIs and access to health services
  • Pregnant women with syphilis and access to health services

Voluntary counseling and testing (VCT)

  • Current sexually active population

Workplace interventions

  • HIV prevention activities for males and females in formal employment
  • STI treatment: same groups as those for strengthening STI services, but limited to workplaces that have STI treatment
  • Condom distribution: the number of sex acts requiring a condom (set at 100% casual and 2% regular partnerships) for those in formal employment

Strengthening blood transfusion services

  • Units of blood used in transfusions

Preventing MTCT

  • Screening (VCT) for pregnant women 15—49 with access to ante-natal services
  • ARV treatment for pregnant women testing HIV positive and formula for infants

Mass media

  • National campaigns for entire country

Palliative care

  • PLHAs who are symptomatic

Clinical management for opportunistic illnesses

  • PLHAs with access to health services

Home-based care

  • PLHAs with access to health services

Clinical care for children

  • Includes palliative care for all children who are HIV positive and symptomatic, and clinical care for children who are HIV positive and symptomatic with access to health services

Prevention of OIs (Cotrimoxazole and TB preventive therapy)

  • PLHAs who are symptomatic and have access to health services

Support for orphans

  • All AIDS orphans less than 15 years old

Psychosocial support and counseling

  • PLHAs who are symptomatic

Treatment (HAART)

  • PLHAs who are symptomatic and have access to health services

ECR Costing Step 3: Consider Existing Implementation Constraints
Planning involves looking at the expected coverage of target groups that can be achieved by 2005. It assumes that the feasibility of expanding coverage of target groups will be higher in countries with strong HIV/AIDS programs than in countries where programs are more challenged and/or fragmented.

Applying the Potential Target Group (PTG) Concept to MTCT Interventions

Defined target group for MTCT interventions is pregnant women attending antenatal facilities.

Once the target group is defined, the coverage of a target group by specific interventions needs to be determined. In this MTCT example, two interventions related to MTCT were costed:

  • VCT among the antenatal population who receive antenatal services, and
  • delivery of antiretroviral/feeding intervention.

Coverage levels for these interventions are the proportion of women being tested for HIV and the proportion of women who agree to take the antiretroviral (ARV) drug regimen. Specific assumptions are then made concerning these two proportions. In the case of care, countries are classified by the strength of their existing HIV/AIDS programs.

The coverage of HIV/AIDS programs will depend on institutional characteristics, particularly the strength of existing programs. For example, African countries are classified into four categories by strength of existing HIV/AIDS programs: very low, low, medium and strong HIV/AIDS programs. Strong program countries include Uganda and Senegal, which have slowed the HIV epidemic. "Very low" program countries include those that are currently in conflict, such as Liberia and Eritrea, or those where conflict has only recently stopped, such as Somalia. This classification is shown in Table 3.

The potential coverage of HIV/AIDS interventions thought to be feasible to achieve by 2005 is projected for interventions and activities in Table 4. Because of the paucity of information about current levels of coverage for care activities, baseline coverage for care strategies cannot be estimated. Instead, potential increases in coverage for care that could be achieved between 2000 and 2005 are estimated, taking into account the ability of current health systems to absorb a higher level of activity (Table 5).

It is important to note that these percentages are approximations. For each intervention/activity, the proposed increase in coverage from baseline to 2005 is based on what is realistically achievable in a five-year time period, according to capacity and infrastructure constraints. Given the low levels of coverage among the PTGs, these figures reveal that large sections of the population could be reached by existing infrastructures within countries.

ECR Costing Step 4: Estimate Costs
Facility- or project-level cost data are taken from published and unpublished literature to obtain baseline average costs for delivery of each type of program or activity. The costs of expanding or scaling-up interventions are based on current and projected (year 2005) target levels of coverage. The model estimates costs associated with different levels of coverage for PTGs. Planners and program managers can consider these estimated costs in relation to the PTG because they depend on the projected level of coverage sought.

Unit cost data are calculated when estimating costs:

  • Financial costs represent actual expenditure on goods and services purchased. Costs are described in terms of how much money is being paid for the resources used in the program or service.
  • Economic costs include the estimated value of goods or services for which there were no financial transactions. They also pertain to situations in which the price of the good did not reflect the cost of using it productively elsewhere, including donated goods and services and other inputs whose prices may not be accurate.

Table 3: Estimated Strength of HIV/AIDS Program Activities by Countries

Very Low

Low

Medium

Strong

Angola
Congo
DR Congo
Djibouti
Eritrea
Ethiopia
Liberia
Nigeria
Sierra Leone
Somalia

Benin
Burkina Faso
Burundi
Chad
Equatorial Guinea
Gabon
Gambia
Ghana
Guinea
Guinea Bissau
Madagascar
Mali
Mauritius
Niger
Rwanda
Togo

Botswana
Cameroon
Central African Rep.
Côte d'Ivoire
Kenya
Lesotho
Malawi
Mauritania
Mozambique
Namibia
South Africa
Swaziland
Tanzania
Zambia
Zimbabwe

Senegal
Uganda

Note: Due to a lack of data, countries in italics are not included in estimates presented in Tables 4 and 5.

Analyzing costs can be done in two ways:

  • Full cost analysis estimates the costs of all resources that are used to run a program or service, including basic infrastructure.
  • Incremental analysis looks at the cost of adding the additional program or service to existing ones.

When calculating unit cost data, all prevention and basic care costs are best determined from the perspective of the provider. Where possible, consider economic costs and full cost analysis. Unless indicated, all unit costs include recurrent and annualized costs for capital inputs. A detailed review regarding the costs of prevention is found in Kumaranayake and Watts (2000b). For purposes of this analysis, countries classified as high income are Botswana, Djibouti, Gabon, Mauritius, Namibia, South Africa and Swaziland.

Table 6 describes unit cost by intervention. Planners and program managers can use these data to develop cost estimates for interventions at the national, district and/or community levels.

Table 4: Proposed Estimates of Baseline and Target Levels of Coverage for 2005 for HIV/AIDS Interventions (by Program Strength)

 

Coverage Estimates for HIV/AIDS Interventions

 

Baseline Coverage Estimate

 
 

Very Low

Low

Medium

Strong

Very Low

Low

Medium

Strong

Youth interventions

% required primary teachers trained

5%

5%

10%

20%

40%

50%

60%

60%

% required secondary teachers trained

20%

20%

30%

50%

60%

70%

80%

80%

% out-of-school youth reached aged 6—11

5%

5%

10%

10%

10%

10%

15%

15%

% out-of-school youth reached aged 12—15

5%

5%

10%

20%

30%

40%

50%

50%

Interventions focused on sex workers and clients

% sex workers reached by intervention per year

20%

20%

40%

50%

40%

50%

60%

60%

Average consistency of condom use

20%

25%

30%

30%

50%

60%

70%

80%

% female condoms

5%

5%

5%

5%

5%

5%

5%

5%

Increased public sector condom provision

% of sex acts in which public sector condoms used

5%

10%

20%

30%

10%

20%

30%

40%

Condom wastage during storage & distribution

10%

10%

10%

10%

10%

10%

10%

10%

Condom social marketing

% of sex acts in which CSW used condoms

5%

10%

20%

30%

30%

40%

50%

50%

% of CSW female condoms provided

10%

10%

10%

10%

10%

10%

10%

10%

Improving STI services

% male symptomatic STIs treated at clinics

5%

5%

15%

20%

30%

30%

30%

40%

% female symptomatic STIs treated at clinics

5%

5%

15%

20%

30%

30%

30%

40%

% syphilis among ANC women detected and treated

5%

5%

15%

20%

30%

30%

40%

50%

Voluntary counseling and testing

Urban coverage sexually active aged 15—49

1%

1%

1%

1%

5%

5%

5%

5%

Rural coverage sexually active aged 15—49

0%

0%

0%

0%

5%

5%

5%

5%

Workplace interventions (including military, truckers)

% workforce with access to HIV peer education

0%

2%

10%

10%

10%

10%

25%

25%

% total condoms provided by workplace

5%

10%

20%

30%

60%

60%

60%

60%

% workforce employers providing STI treatment

1%

1%

5%

5%

5%

5%

15%

15%

% men in workplace, symptomatic STIs treated

1%

1%

5%

5%

80%

80%

80%

80%

% women in workplace, symptomatic STIs treated

1%

1%

5%

5%

40%

40%

40%

40%

Blood safety measures

Proportion units of blood for transfusion tested, urba

60%

80%

95%

100%

100%

100%

100%

100%

Proportion units of blood for transfusion tested, rural

40%

70%

90%

100%

80%

95%

100%

100%

MTCT interventions

% urban pregnant women attending ANC in facility tested

0.5%

0.5%

0.5%

0.5%

10%

10%

10%

10%

% rural pregnant women attending ANC in facility tested

0%

0%

0%

0%

5%

5%

5%

5%

% women offered regimen request and complete

0%

0%

0.5%

0.5%

90%

90%

90%

90%

% women testing HIV positive take formula

0%

0%

0.5%

0.5%

50%

50%

50%

50%

Mass media

Average number of campaigns per year

2

2

2

2

6

6

6

6

Table 6. Description of Source of Unit Cost Estimates
Note: 1) For all cost scenarios, activities are coordinated primarily through the ministries of education. 2) There is no available information regarding the costs of primary school education for Tanzania, other than approximations by Boerma and Bennett (1997).

Table 5: Proposed Percentage Increase in Coverage for Basic HIV/AIDS Care by 2005

 

Country Program Strength

 

Very Low

Low

Medium

Strong

Palliative care

Proportion of symptomatic people receiving palliative care

40%

40%

30%

30%

Clinical management of opportunistic illnesses

Proportion of symptomatic people requiring clinical management of OIs with access to health services receiving care

20%

20%

20%

20%

Prevention of OIs

Proportion of symptomatic people with access to health services who are receiving palliative care

25%

25%

35%

35%

Home-based care

Proportion of PLHA receiving home-based care

20%

20%

20%

20%

Care for HIV-positive infants

Proportion in last year of life receiving palliative treatment

40%

40%

30%

30%

Proportion requiring care for opportunistic infectionswith access to health services receiving care

20%

20%

20%

20%

Care for orphans

Proportion of orphans in orphanages

5%

5%

5%

5%

Proportion of orphans in community receiving assistance

5%

5%

15%

20%

Proportion of all orphans receiving subsidy for school educatio

5%

5%

15%

20%

Psychosocial support and counseling

Proportion of PLHA cases receiving psychosocial support

15%

30%

30%

15%

Treatment

HAART

10%

10%

25%

25%

 

Table 6: Source of Unit Cost Estimates

Youth Interventions

Cost per teacher trained, primary school education

Low:

$75; simple program with teacher training and provision of basic material

Medium:

$200; includes development of training materials and establishment of school curriculum

Cost per teacher trained, secondary school education

Low:

$121; simple program; assumed to be financial and incremental cost; (Boerma and Bennett 1997), Tanzania

Medium:

$241; more extensive program; assumed to be financial and incremental cost, Tanzania

Cost per youth targeted/peer education for out-of-school youth

Assumed a peer education program in place for out-of-school youth. Given the lack of data, it was assumed that the costs would be higher than for a workplace intervention but lower than for a commercial sex worker (CSW) intervention because clients are easier to reach. The cost calculations are an average of the relevant scenarios for the CSW and workplace peer education programs.

Low:

$8.00

Medium:

$10.81

Sex Worker Interventions

Cost per CSW targeted

Peer education project in Cameroon, educators not salaried and condoms not freely distributed; economic and full costing (Kumaranayake et al. 1998)

Low:

$15.83

Medium:

$21.12

Cost per male condom distributed, urban

Costs from a CSW program in Zimbabwe; assumed to be economic costing (Soderlund et al. 1993); this provided a figure for the medium scenario, extrapolated for low cost.

Low:

$0.10

Medium:

$0.14

Cost per female condom distributed

Commodity and marketing/distribution costs from existing Population Services International (PSI) CSW programs in Zambia and Zimbabwe (personal communication, Guy Stallworthy); financial and incremental costs

Low:

$1.00

Medium:

$2.00

These figures include estimates of market and distribution costs associated with the female condom. The negotiated wholesale price for the female condom is about $0.64 in 2000 prices. Marketing is much more intensive for the female condom than for the male condom.

Note: 1) For all cost scenarios, activities are coordinated primarily through the ministry of education. 2) There is no available information regarding the costs of primary school education for Tanzania, other than approximations by Boerma and Bennett (1997).

Increased Public Sector Condom Distribution

 

Taken from Zambia, where condoms were distributed free of charge through public channels; economic and full costing (Goodman and Watts 1995); both urban and rural costs are assumed to be the same.

Cost per male condom distributed in the public sector

Low:

$0.10

Medium:

$0.34

Cost per male condom for strengthening condom logistics

Low:

$0.045

Medium:

$0.07

Condom Social Marketing

 

Figures were taken from Stallworthy and Meekers (1998), which presented range of costs for PSI's CSW programs by low-, medium- and high-cost programs in 1996 dollars; assumed to be financial and full cost.

Cost per male condom distributed, urban

Low:

$0.12

Medium:

$0.29

Cost per male condom distributed, rural

Low:

$0.25

Medium:

$0.45

Cost per female condom distributed

Same as for cost per female condom distributed in CSW interventions

Improving STI Services

Cost per STI case treated/visited (syndromic management)

Low:

$12.65; intensified intervention through existing health services in Tanzania with syndromic management; economic and incremental (Gilson et al. 1997)

Medium:

$15; integrated STI/HIV control program in Mozambique; included costs for pre-consultation, partner notification, syndromic management, but excluded planning and management; assumed to be financial and incremental (Bastos et al. 1992)

Cost per woman screened for syphilis in reproductive health services

Low:

$0.91; cost per woman screened in Tanzania, assumed to be financial (Kigadye et al. 1993)

Medium:

$2.00 from Mozambique program described above (Bastos et al. 1992).

Cost per STI case treated, ANC service

Same as for cost per STI case treated/visited

VCT

Cost per person counseled and tested

Low:

$3.80; cost of adding VCT to a rural South African hospital, excluding all overhead costs, but including all commercial costs of test kits, laboratory staff and equipment used; rapid Capillus test, economic and incremental

Medium:

$13.82; estimated costs of running VCT in freestanding clinic in Uganda (Alwano-Edyegu and Marum 1999); assumed to be economic and full

Workplace Interventions

 

The unit cost data for peer education are taken from Soderlund et al. (1993) and come from a workplace intervention in Uganda. Figures are taken for low cost and are extrapolated upward to obtain a medium cost; assumed to be economic and full costing.

Cost per person in employment reached (peer education)

Low:

$0.26

Medium:

$0.50

Cost per STI case treated/visited

As per strengthening STI treatment

Cost per male condom distributed

As per CSW intervention

Strengthening Blood Transfusion System

 

The unit cost data are derived from Soderlund et al. (1993). These figures are based on national and centralized blood transfusion systems in Zimbabwe and Uganda; assumed to be full and economic costing.

Cost per safe unit collected

Low:

$5.34

Medium:

$18.22

MTCT

Cost per woman screened

As per VCT intervention; all these costs are just the drug cost

Cost per woman testing HIV positive and receiving regimen

Low:

$5; HIVNET 012 Nevirapine regimen; cost per course based on dose given to women at labor and then dose for infant after birth, based on Marseille et al. (1999); assumed to be financial and incremental

Medium:

$50; CDC Thai – ZDV only pre- and intrapartum. Cost per course if using Thai generically manufactured drug (UNAIDS, 1999b); no inclusion of freight costs just the drug prices; assumed to be financial and incremental

Cost of strengthening delivery services in facilities to undertake regimen per woman testing HIV positive

The cost of providing training and additional staff to meet these needs is extrapolated; these costs are derived from Wilkinson et al. (1998), and are based on the costs of additional nurse training and midwives in rural South Africa.

Low:

$13.70 – 40% of Wilkinson et al. (1998) costs

Medium:

$24.00 – 70% of Wilkinson et al. (1998) costs

Cost per woman of six months of formula milk

Low-cost data from Pazvakavambwa (1999). Assumed to be financial and incremental; do not include freight and transport costs; medium cost is extrapolated from low price; costs of ensuring access to safe water are not included.

 

Low:

$50

 

Medium:

$55

Mass Media

Cost per campaign

The cost data for mass media campaigns come from Soderlund et al. (1993) and Kumaranayake et al. (1998). Both are economic and full cost. The low-cost scenario corresponds to a program in Gabon, where the campaign was contracted to a private firm and includes salary and overheads; the medium-cost scenario relates to a mass media program run for three months in Cameroon, paying commercial rates for broadcast time; this excludes overhead costs and salaries of people involved.

 

Low:

$489,565

 

Medium:

$516,817

Palliative Care

Cost per patient year

These costs are based on the estimated frequency of these symptoms for PLHA in sub-Saharan Africa and the drug costs of treating common symptoms (such as fever, cough, diarrhea, skin rashes, headaches, nausea), which are used to derive a cost per patient year; assumed to be economic and incremental (World Bank 1997a).

Low:

$21.50

Medium:

$25.80

Clinical Management of OIs

Cost per adult per year of treatment

The costs of clinical management include the costs of treating common opportunistic infections (OIs) in sub-Saharan Africa (such as tuberculosis, oral thrush, pneumonia/septicemia). The cost is based on the estimated frequency of OI, drug costs and costs of inpatient and outpatient care in sub-Saharan Africa. The cost of the drugs is taken from the World Bank (1997a). Costs of inpatient and outpatient facilities were estimated separately for low-income countries (based on World Bank 1997a; Hansen et al. 2000). These costs include both direct patient-related costs (drugs and laboratory services) and indirect costs (staff and facility costs). To obtain figures for high-income countries, multipliers are calculated for direct and indirect costs based on the relative costs of ambulatory and inpatient TB treatment in South Africa (Floyd et al. 1997), Malawi, Mozambique and Tanzania (De Jonghe et al. 1994); assumed to be economic and full cost.

Low-income countries:

 

Low:

$247

Medium:

$359

High-income countries:

 

Low:

$471

Medium:

$698

Prevention of Opportunistic Infections (OIs)

Cost per adult per year of prophylaxis for OI (INH and Cotrimoxazole)

Given the duplication of activities in providing preventive TB therapy and Cotrimoxazole (monitoring, costs of outpatient visits), the joint costs of administering INH and Cotrimoxazole are estimated. For low-income countries, cost data are adapted from Aisu et al. (1995) in Uganda for six months of INH preventive therapy and include costs of initial skin test, screening (chest X-ray, sputum smears) for active TB and personnel and administration costs. High-income country costs are adapted from Masobe et al. (1995) in South Africa and include costs of testing, administration of drugs (INH five times a week for six months), monitoring and personnel and transport costs. Data related to the cost of Cotrimoxazole are taken from Guinness (2000). No additional costs for HIV testing are included, because they were assumed to be included in costs related to VCT; costs are assumed to be financial and incremental.

 

Low-income countries:

 
 

Low:

$30

 

Medium:

$36

 

High-income countries:

 
 

Low:

$64

 

Medium:

$79

Home-based Care

Cost per person living with HIV/AIDS supported

The cost estimates come from projects in Zimbabwe and Zambia (Chela et al. 1994; Gilks et al. 1998). They are from interventions that tend to have a very low coverage among their target populations (less than 10% of the eligible population in Zambia and Zimbabwe); assumed to be financial and full cost.

 

Low:

$63

 

Medium:

$197

Care for HIV-positive Children

Cost of palliative care per child

Taken to be two-thirds of the costs of care of adults

 

Low:

$14.30

 

Medium:

$17.20

Cost of clinical management of OI per child

Low-income countries:

 

Low:

$163

 

Medium:

$237

 

High-income countries:

 
 

Low:

$311

 

Medium:

$461

Support for Orphans

Cost per child in an orphanage

Living expenses include food, clothing and basic commodities. School expenses include subsidies for fees and uniforms. Based on estimates from Boerma and Bennett (1997) for orphanage care in Tanzania; assumed to be financial and full cost.

 

Low:

$120

 

Medium:

$180

Cost per child for community assistance with living expenses

Taken from Drew et al. (1998) for programs in Zimbabwe, implemented by community-based organizations, using volunteers who visit families with orphans; cost assumed to be financial and full.

 

Low:

$9

 

Medium:

$35

 

Derived from Boerma and Bennett (1997), in the context of district-based programs for communities in a high-prevalence setting. This includes support to new orphans and community feeding posts; cost assumed to be financial and full.

Cost per child for school expenses

Based on estimates from Boerma and Bennett (1997) for Tanzania. Weighted average of primary and secondary school costs; assumed to be financial and full cost.

 

Low:

$25

 

Medium:

$33

Psycosocial Support and Counseling

Cost per person reached

Costs are extrapolated from VCT cost. There are no published estimates of costs.

 

Low:

$3

 

Medium:

$6

Institutional Strengthening

 

These costs are related to existing program strength (very low, low, medium and strong) and are based on estimates for implementation of the MTP-III in Tanzania.

Cost per capita for very low-program-strength countries

Low:

$0.021

Medium:

$0.026

Cost per capita for low-program-strength countries

Low:

$0.015

Medium:

$0.019

Cost per capita for medium-program-strength countries

Low:

$0.010

Medium:

$0.013

Cost per capita for strong-program-strength countries

Low:

$0.006

Medium:

$0.008

Treatment (HAART)

Cost per person treated with triple combination therapy

The structure for calculating the costs of HAART follows the UNAIDS Care Model (UNAIDS 2000a). The cost per person includes the costs of drugs, monitoring, staff training, transport, strengthening of facilities for administration of ARV treatment, and appropriate clinical management and provision of drugs to deal with side effects and adverse reactions and basic pain relief, as well as prophylaxis for OIs. The largest component of the unit cost is the cost of the drugs. These prices change rapidly and reflect the different combinations of drugs that may be prescribed. For the low-cost scenario, an average drug price of $1,400 (US) per person annually is used. This is based on recent negotiations between Senegal and the pharmaceutical companies related to the bulk buying of ARV (Drug Companies 2000). The drug price for the medium-cost scenario is $2,635 (US), based on the 1999 Brazilian experience with ARV purchases (Panos 2000). By comparison, the negotiated price for Uganda's purchases in May 2000 was $4,201(US), and the price in the United States was $9,905 (US).

The monitoring costs reflect the costs of viral load monitoring, CD-4 cell counts, blood chemistry, transport and outpatient visits drawn from a range of sources (Guinness 2000; Panos 2000; World Bank 1997a). The staff training courses are based on the estimate of Masobe et al. (1995) for the costs of training for implementation of preventive therapy and are adjusted downward for low-income countries based on the ambulatory multiplier for direct costs described above in the calculation of the costs of clinical management. The costs for appropriate clinical management, for drugs to deal with side effects, adverse reactions and basic pain relief, and for prophylaxis for OIs are drawn from the same sources above. Costs are assumed to be financial and incremental.

Low-income countries:

Low:

$1,993

Medium:

$3,468

High-income countries:

Low:

$2,393

Medium:

$4,049

Key Implementation Questions for Costing and Use of Resources

The following is a summary of the key implementation questions for costing and use of resources in Module 6.

Key Implementation Questions for Costing and Use of Resources in ECR

ECR Resource Allocation

  • What criteria are used to allocate resources in your program?
  • Have you considered criteria based on need? Have you prioritized target groups?
  • Have you evaluated or rated the relative strength of your program?
  • Have you considered the cost effectiveness of your ranked interventions? Have you considered the complexity of delivering ranked interventions? Have you considered the per capita cost for delivering ranked interventions?

ECR Costing

  • When costing your ECR plan, have you implemented each of the following steps?
  • Step 1 – Establish size of target groups.
  • Step 2 – Define current and future program coverage.
  • Step 3 – Consider existing implementation constraints.
  • Step 4 – Estimate costs.

Further Reading

Primarily adapted from:
World Bank. Costs of Scaling HIV Program Activities to a National Level in Sub- Saharan Africa: Methods and Estimates. Prepared for the Africa Development Forum, December 2000.

Detailed References

  1. Adler M, Foster S, Grosskurth H, Richens J, Slavin H. Sexually Transmitted Infections: Guidelines for Prevention and Treatment. Health and Population
  2. Occasional Paper. London: Department for International Development, 1998.
  3. Ainsworth M, Teokul W. Breaking the silence: setting realistic priorities for AIDS control in less developed countries. Lancet 2000;356: WA 35–40.
  4. Aisu T, Raviglione MC, van Praag E, et al. Preventive chemotherapy for
  5. HIV-associated tuberculosis in Uganda: An operational assessment at a voluntary counseling centre. AIDS 1995;9: 267—73.
  6. Alwano-Edyegu M, Marum E. Knowledge Is Power: Voluntary Counseling and Testing in Uganda. Geneva: UNAIDS, 1999.
  7. Bastos dos Santos R, Folgosa EMP. Fransen L. Reproductive Tract Infections in Mozambique: A Case Study of Integrated Services. In A. Germain, et al., eds. Reproductive Tract Infections: Global Impact and Priorities for Women's Reproductive Health. New York: Plenum Press, 1992.
  8. Bell JC, Rose DN, Sacks HS. Tuberculosis preventive therapy for HIV infected people in sub-Saharan Africa is cost-effective. AIDS 1999;13: 1549—56.
  9. Binswanger H P. Scaling up HIV/AIDS programs to national coverage. Science 2000;288: 2173—5.
  10. Boerma, T, Bennett J. Costs of district AIDS programmes. In J Ng'weshemi, T Boerma, J Bennett, D Schapink, eds. HIV Prevention and Aids Care in Africa 21: 353—70. Amsterdam: Royal Tropical Institute, 1997.
  11. Broomberg J, Söderlund N, Mills A. Economic analysis at the global level: A resource requirement model of HIV prevention in developing countries. Health Policy 1996; 38: 45—65.
  12. Bureau of Statistics (Tanzania), Macro International Inc. Trends in Demographic, Family planning, and Health Indicators in Tanzania. Calverton, Md.: Bureau of Statistics and Macro International, Inc., 1997
  13. Chela CM with Msiska R, Sichone M, Mwinga B, Marin A, Yamba CB, Anderson S, Van Pragg E. Cost and Impact of Home-Based Care for People Living With HIV/AIDS in Zambia 1994. Ministry of Health, Zambia, and Global Programme on AIDS, World Health Organization, 1994.
  14. Colebunders R, Karita E, Taelman H, Mugyenyi P. Antiretroviral treatment in Africa. AIDS 1997;11 (Suppl. B): S107—13.
  15. Costello Daly C, Franco L, Chilongozi DAT, Dallabetta G. A cost comparison of approaches to STD treatment in Malawi. Health Policy and Planning 1998;13 (1): 87—93.
  16. Cohen J. Is AIDS in Africa a Distinct Disease? Science 2000;258: 2153—5.
  17. Creese A, Parker D, eds. Cost Analysis in Primary Health Care: A Training Manual for Programme Managers. WHO: Geneva, 1994.
  18. De Jonghe E, Murray CJL, Chum HJ, et al. Cost-effectiveness of chemotherapy for sputum smear-positive pulmonary tuberculosis in Malawi, Mozambique and Tanzania. International Journal of Health Planning and Management 1994;9: 151—81.
  19. Drayton J. World Bank HIV/AIDS Interventions: Ex-Ante and Ex-Post Evaluation. World Bank Discussion Paper No. 389. Washington, D.C.: World Bank, 1998.
  20. Drew RS, Makufa C, Foster G. Strategies for providing care and support to children orphaned by AIDS. AIDS Care 1998;10 (Suppl.): S9—15.
  21. Drug Companies, Senegal Agrees to Low Cost HIV Drug Pact. Wall Street Journal (Oct. 24, 2000).
  22. Floyd K, Gilks C. Cost and Financing Aspects of Providing Anti-Retroviral Therapy: The Implications of Anti-Retroviral Treatments. WHO: Geneva, 1997.
  23. Floyd K, Wilkinson D, Gilks CF. Community-Based, Directly Observed Therapy for Tuberculosis: an Economic Analysis. Cape Town: South African Medical Research Council, Corporate Communications Division, 1997.
  24. Forsythe SS. The affordability of antiretroviral therapy in developing countries: What policymakers need to know. AIDS 1998;12 (Suppl. 2): S11—18.
  25. Foster G, Makufa C, Drew R, Kambeu S, Saurombe K. Supporting children in need through a community-based orphan visiting programme. AIDS Care 1996;8 (4): 389—403.
  26. Foster G, Shakespeare R, Chinemana F, Jackson H, Gregson S, Marange C, Mashumba S. Orphan prevalence and extended family care in a Peri-Urban community in Zimbabwe. AIDS Care 1995;7 (1): 3—17.
  27. Foster S. Supply and use of essential drugs in sub-Saharan Africa: Some issues and possible solutions. Social Science and Medicine 1991;32 (11): 1201—18.
  28. Gerbase A. Estimates of Curable Untreated STIs. Unpublished data, 1999.
  29. Gilks C, Floyd K, Haran D, Kemp J, Squire B, Wilkinson D. Care and Support for People with HIV/AIDS in Resource-Poor Settings. London: Department for International Development, 1998.
  30. Gilks CF, Katabira E, De Cock, K. The challenge of providing effective care for HIV/AIDS in Africa. AIDS 1997;11 (Suppl.): S9—106.
  31. Gilson L, Mkanje R, Grosskurth H, Mosha F, Picard J, Gavyole TJ, Mayaud P, Swai R, Fransen L, Mabey D, Mills A., Hayes R. Cost-effectiveness of improved treatment services for sexually transmitted diseases in preventing HIV-1 infection in Mwanza Region, Tanzania. Lancet 1997;350: 1805—9.
  32. Goodman H, Watts C. Resource Allocation for HIV Prevention: Report on Pilot Study in Zambia. Report for WHO/GPA, 1995.
  33. Grant AD, Djomand G, De Cock KM. Natural history and spectrum of disease in adults with HIV/AIDS in Africa. AIDS 1997;11 (Suppl. b): 43—54.
  34. Grosskurth H, Mosha F, Todd J et al. Impact of improved treatment of STD treatment on the HIV epidemic in rural Tanzania. Lancet 1995;346: 530—6.
  35. Guinness L. Economic Analysis of Cotrimoxazole Prophylaxis in PLHA. Presentation. Durban, South Africa, 2000.
  36. Hansen K, et al. The costs of hospital care at government health facilities in Zimbabwe with special emphasis on HIV/AIDS patients. Health Policy and Planning 2000;15 (4).
  37. Kamali A, et al. The orphan problem: Experience of a sub-Saharan Africa population in the AIDS epidemic. AIDS Care 1996;8 (5): 509—15.
  38. Kerkhoven R, Jackson H. Community Care: Not Just in the Home. Harare, Zimbabwe: SAfAIDS, 1997.
  39. Kigadye RM, Klokke A, Nicoll A, Nyamuryekung'e KM, Borgdorff M, Barongo L, Laukamm-Josten U, Lisekie F, Grosskurth H, Kigadye F. Sentinel surveillance for HIV-1 among pregnant women in a developing country: Three years' experience and comparison with a population serosurvey. AIDS 1997;7 (6): 849—55.
  40. Kritski AL. Tuberculosis preventive therapy for HIV-infected persons in less developed countries. Int Journal Tuberc Lung Dis 2000;4 (2): S76—81.
  41. Kumaranayake L, Mangtani P, Boupda-Kuate A, Foumena Abada J C, Cheta C, Njoumemi Z, Watts C. Cost-Effectiveness of a HIV/AIDS Peer Education Programme among Commercial Sex Workers: Results from Cameroon. Presentation at the XII World AIDS Conference. Geneva, June 28—July 3, 1998.
  42. Kumaranayake L, Pepperall J, Goodman H, Mills A, Walker D. Costing Guidelines for HIV/AIDS Prevention Strategies. UNAIDS Best Practice Collection–Key Materials, 2000 (http://www.unaids.org/Revised/cube_frame.html).
  43. Kumaranayake L, Watts C. Scaling-up Priority Health Programmes: A Problem of Constrained Optimisation. LSHTM, 2000a.
  44. Kumaranayake L, Watts C. Economic costs of HIV/AIDS prevention activities in sub-Saharan Africa. AIDS 2000b;14 (Suppl. 3): S239—52.
  45. Kumaranayake L, Watts C, Vickerman P, et al. Cost-effectiveness of a School Education Program for HIV Prevention: Results from Cameroon. XI International Conference on AIDS and STDs in Africa, Lusaka (abstract 13DT2-2), Sept. 1999.
  46. Lim JY, Chew BW, Phua, KH. An economic analysis of AIDS – towards a proposed model of costing: A Singapore experience. Asia-Pacific Journal of Public Health 1994;7 (3): 143—50.
  47. Marseille E, Kahn JG, Mmiro F, Guay L, Musoke P, Fowler MG, Jackson JB. Cost-effectiveness of single-dose Nevirapine regimen for mothers and babies to decrease vertical HIV-1 transmission in sub-Saharan Africa. Lancet 1999;354: 803—9.
  48. Marseille E, Kahn, JG, Saba, J. Cost-effectiveness of antiviral drug therapy to reduce mother-to-child HIV transmission in sub-Saharan Africa. AIDS 1998;12 (8):939-48.
  49. Masobe P, Lee T, Price M. Isoniazid prophylactic therapy for tuberculosis in HIV-seropositive patients – a least cost analysis. South African Medical Journal 1995;85 (2): 75—81.
  50. Mayaud P, Grosskurth H, Dhangalucha J, Todd J, West B, Gabone R, Senkoro K, Rusizoka M, Alga M, Hayes R, Mabey D. Risk assessment and other screening options for gonorrhoea and chlamydial infections in women attending rural Tanzanian antenatal clinics. Bulletin of the World Health Organization 1995;73 (5): 621—630.
  51. Ministry of Health, Tanzania. Strategic Framework for the Third Medium Term Plan (MTP-III) for Prevention and Control of HIV/AIDS/STDs 1998-2002. The United Republic of Tanzania, National Aids Control Programme, 1995.
  52. Mangtani P. Epidemiological and Behavioral Analysis of a Peer Education Intervention among Commercial Sex Workers and Their Clients: Field-Report from Cameroon. Report prepared for GPA/UNAIDS, 1996.
  53. Munguti K, Grosskurth H, Newell J, Senkoro K, Mosah F, Todd J, Mayaud P, Gavyole A, Quigley M, Hayes R. Patterns of sexual behavior in a rural population in North-Western Tanzania. Social Science and Medicine 1997;44 (10): 1553—61.
  54. O'Brien RJ, Perriens JH. Preventive therapy for tuberculosis in HIV infection: The promise and the reality. AIDS 1995;9: 665—73.
  55. Osborne CM, van Praag E, Jackson H. Models of care for patients with HIV/AIDS. AIDS 1997;11 (Suppl.): S135—42.
  56. Over M. The effect of scale on cost projections for a primary health care program in a developing country. Social Science and Medicine 1986;22 (3): 351—60.
  57. Over M. Coping with the impact of AIDS. Finance and Development March 1998;22—24.
  58. Over M. The Public Interest in a Private Disease: An Economic Perspective on the Government Role in STD and HIV Control. In KK Holmes, PF Sparling, P-A Mardh, SM Lemon, WE Stamm, P Piot, JN Wasserheit, eds. Sexually Transmitted Diseases. New York: McGraw Hill, 1999.
  59. Panos Institute. Beyond Our Means? The Cost of Treating HIV/AIDS in the Developing World. London: Panos Institute, 2000.
  60. Pazvakavambwa B. Estimates of Supply Needs to Support PMTCT 1999-2008: Assumptions. Draft (1999).
  61. Rowley JT, Anderson RM. Modeling the impact and cost-effectiveness of HIV prevention efforts. AIDS 1994;8 (4):539-48.
  62. Scitovsky AA, Over M. AIDS: Costs of care in the developed and the developing world. AIDS 1988;2 (Suppl. 1): S71—81.
  63. Smith JB, Lewis J. The female condom. IPPF Medical Bulletin 1998;32 (3):1—2.
  64. Söderlund N, Broomberg J, Lavis J, Mills A. The costs of HIV/AIDS prevention strategies in developing countries. WHO Bulletin 1993;71 (5): 595—604.
  65. Soderlund N, Zwi K, Kinghorn A, Gray G. Prevention of vertical transmission of HIV: Analysis of cost effectiveness of options available in South Africa. British Medical Journal 1999318:1650.
  66. Stallworthy G, Meekers D. An Analysis of Unit Costs in Selected Condom Social Marketing Programs, 1990—1996." Presentation at the XII World AIDS Conference, Geneva, June 28—July 3, 1998.
  67. Stover J. The Expected Child Survival Benefits of Programs to Reduce Mother-to-Child Transmission of HIV. Paper presented at 1999 annual meeting of the Population Association of America, 1999.
  68. Stover J, Bollinger L. The Economic Impact of AIDS in Africa. Glastonbury, Conn.: The Futures Group International, 1999.
  69. Strathdee SA, van Ameijden EJC, Mesquita F, Wodak A, Rana S. Vlahov D. Can HIV epidemics among injections drug users be prevented? AIDS 1988;12 (Suppl. A): S71—9.
  70. Sweat M, Sangiwa G, Balmer D. HIV counseling and testing in Tanzania and Kenya is cost-effective: Results from the voluntary HIV counseling and testing study. Int Conf Aids 1998;12: 648 (abstract 580/33277).
  71. UNAIDS. HIV-Related Opportunistic Diseases: UNAIDS Technical Update. Geneva: UNAIDS, 1998a.
  72. UNAIDS. Report on the Global HIV/AIDS Epidemic. Geneva: UNAIDS/WHO, 1998b.
  73. UNAIDS. AIDS Epidemic Update: December 1999. Geneva: UNAIDS/WHO, 1999a.
  74. UNAIDS. Prevention of HIV Transmission from Mother to Child. Strategic Options. Geneva: UNAIDS, 1999b.
  75. UNAIDS. Report on the Global HIV/AIDS Epidemic. Geneva: UNAIDS, 2000a.
  76. UNAIDS. UNAIDS/WHO Hail Consensus on Use of Cotrimoxazole for Prevention of HIV-Related Infections in Africa. UNAIDS press release, 2000b. (http:www.unaids.org/whatsnew/press/eng/geneva050400.html).
  77. UNDP. Human Development Report 1995. New York: Oxford University Press, 1996.
  78. UNDP. Human Development Report 1996. New York: Oxford University Press, 1997.
  79. UNDP. Human Development Report 1998. New York: Oxford University Press, 1998.
  80. UNDP. Human Development Report 1999. New York: Oxford University Press, 1999.
  81. UNICEF. The Progress of Nations. New York: UNICEF, 1999.
  82. van de Perre P, Diakhate L, Watson-Williams J. Prevention of blood-borne transmission of HIV. AIDS 1997;11(Suppl.): S89—98.
  83. Van der Veen FH, Ndoye I, Guindo S, Deschampheleire I, Fransen L. Management of STDs and cost of treatment in primary health care centres in Pikine, Senegal. International Journal of STDs and AIDS 1994;5 (4): 262—7.
  84. Watts C. Capture-Recapture as a tool for the evaluation of interventions focused on sex workers and their clients. Ph.D. thesis, London School of Hygiene and Tropical Medicine. Unpublished (1999).
  85. Watts C, Kumaranayake L. Developing Cost-Effectiveness Tools for Decision Makers in Sub-Saharan Africa: Progress and Challenges. Draft (1999a).
  86. Watts C, Kumaranayake L. Thinking big: scaling-up HIV-1 interventions in Sub-Saharan Africa. Lancet 1994b;354: 1492.
  87. Whiteside A, Stover J. The demographic and economic impact of Aids in Africa. AIDS 1997;11 (Suppl. B): S55—62.
  88. Wilkinson D, Floyd K, Gilks CF. Antiretroviral drugs as a public health intervention for pregnant HIV-infected women in rural South Africa: An issue of cost-effectiveness and capacity. AIDS 1998;12: 1675—82.
  89. Wilkinson D, Wilkinson N, Lombard C, Martin D, Smith A, Floyd K, Ballard R. On-site HIV testing in resource-poor settings: Is one rapid test enough? AIDS 1997;11: 377—81.
  90. World Bank. AIDS Prevention and Mitigation in Sub-Saharan Africa: A Strategy for Africa. Report Number 15569. Washington, D.C.: Human Resources and Poverty Division, Technical Department, Africa Region, 1996.
  91. World Bank. Confronting Aids: Public Priorities in a Global Epidemic. New York: Oxford University Press, 1997a.
  92. World Bank. World Development Report 1997. New York: Oxford University Press, 1997b.
  93. World Bank. World Development Report 1998. New York: Oxford University Press, 1998.
  94. World Bank. Intensifying Action Against HIV/AIDS in Africa: Responding to a Development Crisis; Africa Region. Washington, D.C.: World Bank, 1999.
  95. World Bank. World Development Indicators. New York: Oxford University Press, 2000.
  96. World Health Organization. AIDS: Interim proposal for a WHO staging system for HIV infection and disease. Weekly Epidemiological Record 1990;65: 221—8.
  97. World Health Organization. Reproductive Health. WHO/RHT/MSM/96.28. Geneva: WHO, 1996.
  98. World Health Organization. Policy Statement on Preventive Therapy Against Tuberculosis in People Living With HIV. WH0/TB/98.255; UNAIDS 98.34. Geneva: WHO, 1998.
  99. World Health Organization. The World Health Report 2000: Investing in Health Systems. Geneva: WHO, 2000a.
  100. World Health Organization. Blood Safety for too few. Press release. WHO/25 7th April 2000 (http://who.www.who.int), 2000b.
  101. Working Group on Mother-To-Infant Transmission of HIV. Rates of mother-to-infant-transmission of HIV-1 in Africa, America, and Europe: Results from 13 perinatal studies. J Acquir Immun Defic Syndr Retrovirol 1995;8: 506—10.