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Research

Progestin-Only Pills (POPs) FAQ

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What are progestin-only contraceptive pills?
Progestin-only pills (POPs) are pills that are taken once a day to prevent pregnancy. POPs, unlike COCs, do not contain any estrogen.
How do POPs work? (mechanism of action)
  • Thicken cervical mucus (make it hard for sperm to penetrate)
  • Change endometrium (make implantation less likely)
  • Partially inhibit ovulation (in 60% of cycles)
Who can use POPs?
Women of any reproductive age or parity who:
  • Want to use this method of contraception
  • Cannot or should not take pills containing estrogen
  • Are breastfeeding (POPs do not affect the amount or quality of breastmilk)
Who should not use POPs?
Women who have the following conditions (contraindications):
  • Pregnancy
  • Current breast cancer
  • (For more information, see WHO eligibility criteria)
Advantages
  • Safe
  • Effective, especially for breastfeeding women
  • Do not interfere with intercourse
  • Easy to discontinue
  • Immediate return to fertility
  • Have beneficial non-contraceptive effects
Disadvantages
  • Require very strict pill taking schedule (must be taken at the same time every day)
  • Incorrect use is common
  • Require re-supply
  • Have common side effects
  • No protection against STIs/HIV
Possible side effects
More common:
  • Breakthrough bleeding
  • Spotting
  • Irregular cycles
Less common:
  • Nausea
  • Headache
  • Breast tenderness
  • Mood change
  • Weight gain
  • Acne
  • Amenorrhea
Provide follow-up and counseling for:
  • Any client concern
  • Severe abdominal pain (warning sign for ectopic pregnancy)
  • Common side effects
Dispelling myths regarding POPs:
POPs DO NOT:
  • Cause birth defects
  • Cause infertility
  • Require a "rest" period
  • Generally decrease sex drive
  • Build up in a woman's body